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AHK-Cu

Copper Tripeptide-3, Alanine-Histidine-Lysine-Copper, AHK Copper

A copper-binding tripeptide that promotes hair growth, collagen synthesis, and skin rejuvenation by stimulating angiogenesis and fibroblast activity.

Molecular Profile
Formula C15H25CuN6O4
Mol. Weight 416.9 g/mol
Sequence Gly-Glu-Pro-Pro...
Clinical Data Trials
Scientific Data Studies
Route
Topical
0.1-1% in formulations
TOP
Subcutaneous (research)
1-5 mg/kg (animal studies)
SUB

How It Works

How It Works: AHK-Cu functions by complexing with copper ions to enhance cellular processes involved in tissue repair, hair growth, and anti-aging, primarily through modulation of growth factors and extracellular matrix components.

  • Collagen Synthesis: Stimulates fibroblasts to increase production of collagen type I and elastin, improving skin elasticity and reducing wrinkles.
  • Angiogenesis Promotion: Upregulates vascular endothelial growth factor (VEGF) to enhance blood vessel formation and improve nutrient delivery to tissues.
  • Hair Follicle Stimulation: Prolongs the anagen phase of hair growth, increases dermal papilla cell proliferation, and blocks DHT effects.
  • Antioxidant Activity: Supports copper-dependent enzymes like superoxide dismutase (SOD) to reduce oxidative stress and cellular damage.

Pairs Well With

TB
TB-500
Systemic repair
Cu
GHK-Cu
Skin & collagen
KP
KPV
Anti-inflammatory
Ip
Ipamorelin
GH secretagogue

Latest Studies

Utility 2
pubmed 2007

The effect of tripeptide-copper complex on human hair growth in vitro.

Pyo. Hyun Keol HK; Yoo. Hyeon Gyeong HG; Won. Chong Hyun CH; Lee. Seung Ho SH; K...

A tiny copper‑linked peptide called AHK‑Cu was shown in lab tests to help human hair follicles grow longer and to make the special skin cells that control hair (dermal papilla cells) multiply more, while also slightly lowering cell death signals. The work was done in test‑tube and hair‑follicle cultures, not in real people.

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