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Cagrilintide

AM-833, Long-acting amylin analogue

Quick Stats
Studies 57
Trials 38
Completed PHASE1 INTERVENTIONAL NCT06207877

A Research Study to Look at How CagriSema Influences Food Intake, Appetite and Emptying of the Stomach in People With Excess Body Weight

View on ClinicalTrials.gov Updated Dec 15, 2025

Brief Summary

This research study tests if CagriSema influences food intake, appetite and emptying of the stomach in people with excess body weight. Participant will either get CagriSema (active medicine) or placebo (a dummy medicine), which has no effect on the body. The treatment participants get is decided by chance. The study will last for about 32 weeks.

Interventions

Name: Cagrilintide
Type: DRUG
Description: Cagrilintide will be administered subcutaneously.
Name: Semaglutide
Type: DRUG
Description: Semaglutide will be administered subcutaneously.
Name: Placebo
Type: DRUG
Description: Placebo will be administered subcutaneously.

Primary Outcomes

Measure: Relative change in energy intake during ad libitum lunch, evening meal and snackbox
TimeFrame: Baseline to Day 156
Description: Measured in percentage (%).

Trial Information

NCT ID

NCT06207877

Status

Completed

Study Type

INTERVENTIONAL

Phases

PHASE1

Sponsor

Novo Nordisk A/S

Last Updated

December 15, 2025

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