Menu
Submit Data
Peptide Database
Results
No peptides found
Featured

Use search to browse all 100+ peptides

Hexarelin

Examorelin, HEX

A synthetic hexapeptide growth hormone secretagogue that stimulates GH release by acting on the ghrelin receptor in the pituitary and hypothalamus.

Molecular Profile
Formula C47H58N12O6
Mol. Weight 887.0 g/mol
Sequence Gly-Glu-Pro-Pro...
Clinical Data Trials
Scientific Data Studies
Route
Subcutaneous (SC)
1.5-3 mcg/kg
SUB
Intravenous (IV)
1-2 mcg/kg
INT
Intranasal
20 mcg/kg
INT
Oral
20-40 mg
ORA

How It Works

How It Works: Hexarelin functions as a potent agonist at the growth hormone secretagogue receptor (GHS-R), mimicking the action of ghrelin to stimulate growth hormone release from the pituitary gland.

  • Binds to GHS-R1a in the pituitary and hypothalamus, activating signaling pathways that increase GH secretion.
  • Enhances intracellular calcium mobilization and cAMP production, facilitating exocytosis of GH vesicles.
  • May also stimulate release of other hormones like ACTH and prolactin at higher doses.
  • Demonstrates cardioprotective effects potentially independent of GH mediation.

Pairs Well With

TB
TB-500
Systemic repair
Cu
GHK-Cu
Skin & collagen
KP
KPV
Anti-inflammatory
Ip
Ipamorelin
GH secretagogue

Latest Clinical Trials

Recruiting NA NCT07156110

Prosthetic Modality and MBL

Studio Odontoiatrico Associato Dr. P. Cicchese e L. Canullo
INTERVENTIONAL
Updated Dec 15, 2025
Recruiting NA NCT05731882

First in Man Study of Left Atrial Appendage Pulsed Field Ablation Occluder

Hangzhou Dinova EP Technology Co., Ltd
INTERVENTIONAL
Updated Dec 15, 2025
Not Yet Recruiting NA NCT07063615

A Clinical Study to Assess the Safety and Effectiveness of Scalp Cream for Symptom Relief and Microbiome Balance in Mild-moderate Seborrheic Dermatitis Patients.

NovoBliss Research Pvt Ltd
INTERVENTIONAL
Updated Dec 15, 2025
View All Clinical Trials

Latest Studies

Utility 1
pubmed Jul 1, 2025

Identification of alexamorelin consumption biomarkers using human hepatocyte incubations and high-resolution mass spectrometry.

Pobee. Elizabeth E; Daziani. Gloria G; Gameli. Prince S PS; Basile. Giuseppe G;...

The study shows that after taking alexamorelin, the body quickly breaks it down in the liver, turning most of it into a different peptide called hexarelin. This conversion makes it hard to detect alexamorelin use because hexarelin is also sold as its own product, so finding hexarelin in a test doesn't prove someone took alexamorelin.

Utility 2
pubmed Feb 7, 2024

Pharmacological targeting of the hyper-inflammatory response to SARS-CoV-2-infected K18-hACE2 mice using a cluster of differentiation 36 receptor modulator.

Gauvin. Jade J; Huynh. David N DN; Dubuc. Isabelle I; Lê. Catherine C; Tugo...

Researchers gave mice infected with the COVID‑19 virus a synthetic peptide called hexarelin, which can bind to a cell‑surface protein (CD36) that helps drive the harmful inflammation seen in severe disease. In the mouse model, hexarelin changed the behavior of lung immune cells, lowering the flood of inflammatory signals that can cause breathing failure. The work is still early‑stage and done only in animals, so it isn’t a ready‑to‑use treatment for people yet.

Browse All Studies