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Insulin-like Growth Factor 1, Somatomedin C
A 70-amino acid hormone that promotes cell growth, proliferation, and survival, primarily produced in the liver in response to growth hormone stimulation.
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Subcutaneous (SC)
40-120 mcg/kg twice daily
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Intravenous (IV)
40 mcg/kg/hour infusion
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How It Works: IGF-1 acts as an anabolic hormone by binding to specific receptors on cell surfaces, activating signaling pathways that enhance cell growth, metabolism, and survival.
García-Pérez. Isabel I; Rodríguez. Inmaculada I; Rubio. Albert A;...
The paper maps how muscle cells from European sea bass grow and change in a lab dish, tracking many genes including IGF‑1, but it doesn’t give any tips or protocols that people can use for human health or performance.
Ishida. Tomohisa T; Kawaguchi. Tomohiro T; Ogawa. Yoshikazu Y; Endo. Hidenori H
The study looked at people who had surgery for a hormone‑overproduction tumor (acromegaly) and found that even when lab tests for growth hormone and IGF‑1 didn’t match, most patients stayed stable without extra treatment for many years.
Chen. Shuaiming S; Liu. Min M; Tan. Huiwen H; Ji. Lin L; Yu. Yerong Y; Jiang. Sh...
In people with acromegaly, higher IGF‑1 levels were linked to more vertebral fractures, and a special CT scan (QCT) was better at spotting weak bones than the usual DXA scan. This suggests that too much IGF‑1 can hurt bone health, and standard bone density tests might miss the problem.