Procedure for successful interspecific embryo transfer from mouflon (Ovis gmelini musimon) to Spanish Merino sheep (Ovis aries).
Santiago-Moreno. J J; González-Bulnes. A A; Gómez-Brunet. A A; Cocero. M J MJ; del Campo. A A; García-García. R R; López-Sebastián. A A
Key Findings
- Ovagen (FSH‑o) successfully induced superovulation in mouflon donors
- Embryos transferred to selected Merino ewes produced four pregnancies and seven live lambs
- Combining plasma progesterone levels with ultrasound of the corpus luteum helped pick the best recipient ewes
Practical Outcomes
- For the biohacker community, this research offers no actionable protocol for human longevity, metabolism, or performance. It simply shows that Ovagen is used as a reproductive tool in animal breeding, not a supplement for personal health optimization.
Summary
The study used a peptide called Ovagen to boost egg production in wild sheep and then moved those embryos into domestic sheep, resulting in a few successful pregnancies. This is a livestock breeding technique and doesn’t give any direct advice or benefits for human health or performance.
Abstract
Embryos from five anesthetized mouflons (Ovis gmelini musimon), superovulated with FSH-o (Ovagen) were transferred into preselected Spanish Merino sheep (Ovis aries). Myorelaxation was complete in four of five donor mouflons. The status of the uterus of potential recipients was evaluated by transrectal ultrasonography, and those ewes with fluid in the uterine horn were rejected. The corpus luteum in each ewe was assessed ultrasonographically the day before surgery. Plasma progesterone levels and the quality of the corpora lutea were the criteria for selection of recipients. Ten embryos were transferred to the five selected Spanish Merino recipients, resulting in four pregnancies and seven live-born lambs, including three sets of twins. This study shows that determination of plasma progesterone levels combined with ultrasonographic assessment of the corpus luteum provides information useful for screening of potential recipients.
Study Information
pubmed
2001
10.1638/1042-7260(2001)032[0336:pfsiet]2.0.co;2