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Oxytocin

Pitocin, Syntocinon

Quick Stats
Studies 93
Trials 100
Unknown PHASE2, PHASE3 INTERVENTIONAL NCT01477840

Comparative of Effects of Sublingual Misoprostol and Infusion Oxytocin in Reduction of Bleeding at Cesarean

View on ClinicalTrials.gov Updated Dec 15, 2025

Brief Summary

The purpose of this study is to determine whether the effect of sublingual misoprostol is better than infusion oxytocin in reduction of blood loss at cesarean deliveries.

Detailed Description

A total of 180 pregnant women with gestational age 37 weeks and over who underwent cesarean operation in Imam Reza hospital had elective or emergency procedure with incision in lower segment during one year recruitment. The patients were randomly assigned to undergo 200 micrograms misoprostol sublingual or 400 micrograms and infusion 20 unit oxytocin after spinal anesthesia. Main outcome measures: The length of surgery, bleeding volume, the need for transfusion, fever, tachycardia, and hypotension.

Interventions

Name: Misoprostol
Type: DRUG
Description: Sublingual Misoprostol 200 Micrograms After Spinal Anesthesia

Primary Outcomes

Measure: Intraoperative bleeding
TimeFrame: At the time of surgery
Description:

Trial Information

NCT ID

NCT01477840

Status

Unknown

Study Type

INTERVENTIONAL

Phases

PHASE2, PHASE3

Sponsor

Soudabeh Eshghi ali

Last Updated

December 15, 2025