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Oxytocin

Pitocin, Syntocinon

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Studies 93
Trials 100
Completed OBSERVATIONAL NCT01891201

Intrapartum Oxytocin Administration Affects Primitive Neonatal Reflexes

View on ClinicalTrials.gov Updated Dec 15, 2025

Brief Summary

The aim of this study was to assess whether administration of oxytocin intrapartum (Oxt) has any effect on Neonatal Primitive Reflexes (RNP) and if dose dependent. The secondary objective is to assess the effects on exclusive breastfeeding at 3 months

Detailed Description

Patients and Methods Prospective case-control study performed in a tertiary hospital. Cases: mother-child dyads in which Oxt had been administered during the birth process (n = 53). Controls: mother-child dyads without Oxt (n = 45). The RNP were recorded with a camcorder in biological nurturing position. An observer blinded to the group and the dose of Oxt codified the RNP (reach/not reached). To assess the type of breastfeeding telephone call was made at 3 months old RN.

Interventions

Name: Oxytocin
Type: DRUG
Description: Comparison of Primitive Newborn Reflexes between those exposed or not to Oxytocin

Primary Outcomes

Measure: Expression of Neonatal Primitive Reflexes (RNP) are modified by administration of Oxytocin during delivery.
TimeFrame: 72 hours
Description: Neonatal Primitive Reflexes studied were: 1) Endogenous: hand to mouth, extension / flexion of fingers, mouth open, tongue extrusion, arm circular motion, circular motion of the leg, flex foot / hand, 2) Antigravity: raise the head, 3) Motors: turn your head, nod, plantar pressure, Babinski, and 4) Rhythmic: suction, jaw movement and swallowing. An observer, blinded to the study group and the dose administered of Oxytocin, valued recordings, analyzing the state of consciousness at the beginning of the recording as Brazelton scale and form RNP dichotomous coding (achieved / not achieved).

Trial Information

NCT ID

NCT01891201

Status

Completed

Study Type

OBSERVATIONAL

Sponsor

Puerta de Hierro University Hospital

Last Updated

December 15, 2025