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Oxytocin

Pitocin, Syntocinon

Quick Stats
Studies 93
Trials 100
Completed PHASE4 INTERVENTIONAL NCT03308643

Effect of Oxytocin Infusion on Blood Loss During Abdominal Myomectomy

View on ClinicalTrials.gov Updated Dec 15, 2025

Brief Summary

To evaluate the effects of oxytocin infusion during abdominal myomectomy.

Detailed Description

Myomectomy is indicated for symptomatic uterine fibroids. Fibroids have blood supply and 20% of the abdominal myomectomy cases might require blood transfusion because of the nature of the surgery. Oxytocin infusion is one of the intervention to decrease blood loss during myomectomy. To evaluate the effects and benefits of oxytocin infusion during abdominal myomectomy we decide to conduct this randomized study.

Interventions

Name: Oxytocin
Type: DRUG
Description: Patients will receive intravenous oxytocin infusion just before the surgery after the induction of general anesthesia.
Name: saline
Type: OTHER
Description: Patients will receive intravenous normal saline infusion just before the surgery after the induction of general anesthesia.

Primary Outcomes

Measure: Blood loss during surgery
TimeFrame: 2 hours
Description: estimated blood loss during the surgery measured by aspiration fluid.

Trial Information

NCT ID

NCT03308643

Status

Completed

Study Type

INTERVENTIONAL

Phases

PHASE4

Sponsor

Kanuni Sultan Suleyman Training and Research Hospital

Last Updated

December 15, 2025