A study compared waiting 12 hours versus 24 hours after the water breaks before starting oxytocin to induce labor. Waiting the longer time slightly lowered C‑section rates (about 32% less) but the result wasn’t statistically significant, and there were no extra maternal or newborn complications.

To compare the outcomes of 12-hour versus 24-hour latent phase durations in low-risk women with premature rupture of membranes (PROM). This prospective study included 213 women with PROM at &#x2265;37 weeks of gestation, randomized into two groups: 12-hour (<i>n</i> = 142) and 24-hour (<i>n</i> = 71) latent phase management. Participants underwent cervical ripening followed by oxytocin induction. Primary outcomes included cesarean section rates and maternal and neonatal complications. The 24-hour latent phase group showed a clinically relevant but non-significant 32% reduction in cesarean section rates compared to the 12-hour group (OR: 1.32, 95% CI: 0.73-2.38, <i>P</i> = 0.360). No statistically significant differences were observed in maternal complications (emergency cesarean section, atony, chorioamnionitis) or neonatal outcomes (NICU admission, Apgar scores &lt;7) between groups (all <i>P</i> values &gt; 0.05). Nulliparous women had numerically higher but statistically nonsignificant complication rates than multiparous women (all <i>P</i> values &gt; 0.05). Extending the latent phase to 24 hours in carefully selected PROM cases may offer a clinically meaningful reduction in cesarean sections, though this finding was not statistically significant. The approach did not increase maternal or neonatal risks. Parity-specific trends warrant further investigation.