Unknown
PHASE4
INTERVENTIONAL
NCT02933333
G-CSF Alone or Combination With GM-CSF on Prevention and Treatment of Infection in Children With Malignant Tumor
View on ClinicalTrials.gov
Updated Dec 15, 2025
Brief Summary
The purpose of this study is to explore the effect of G-CSF combination with GM-CSF on prevention and treatment of infection in children with malignant tumor.
Detailed Description
G-CSF Alone or Combination With GM-CSF on Prevention and Treatment of Infection in Children With Malignant Tumor.
Interventions
Name:
GM-CSF
Type:
BIOLOGICAL
Description:
Granulocyte-macrophage colony-stimulating factor (GM-CSF) is a hematopoietic CSFs that decrease the duration and severity of neutropenia for patients receiving chemotherapy. GM-CSF is a stimulator of the growth and differentiation of hematopoietic progenitor cells committed to neutrophils, monocytes or eosinophils.
Name:
G-CSF
Type:
BIOLOGICAL
Description:
Granulocyte colony-stimulating factor (G-CSF) is a hematopoietic CSFs that decrease the duration and severity of neutropenia for patients receiving chemotherapy. G-CSF is a relatively specific stimulator of the growth and differentiation of hematopoietic progenitor cells committed to the neutrophil lineage.
Name:
GM-CSF and G-CSF
Type:
BIOLOGICAL
Description:
Granulocyte-macrophage colony-stimulating factor (GM-CSF) and granulocyte colony-stimulating factor (G-CSF) are hematopoietic CSFs that decrease the duration and severity of neutropenia for patients receiving chemotherapy. GM-CSF and G-CSF share a number of biologic activities, GM-CSF seems to be more potent against fungi.
Primary Outcomes
Measure:
assess the incidence of infection in patients after chemotherapy
TimeFrame:
within 20 days after chemotherapy
Description:
Trial Information
NCT ID
NCT02933333
Status
Unknown
Study Type
INTERVENTIONAL
Phases
PHASE4
Sponsor
Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
Last Updated
December 15, 2025