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KEDP, H-Lys-Glu-Asp-Pro-OH
A synthetic tetrapeptide bioregulator researched for prostate health, reducing inflammation, and modulating chromatin structure to normalize age-related cellular changes.
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Intramuscular (IM)
500-1000 mcg daily
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Subcutaneous (SC)
500-1000 mcg daily
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Intramuscular (animal)
0.1 mcg daily (rat models)
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How It Works: Prostamax functions as an epigenetic regulator by promoting chromatin decondensation and gene activation, potentially normalizing age-related changes in prostate and immune cells.
Dzhokhadze. T A TA; Buadze. T Zh TZh; Gaĭozishvili. M N MN; Baratashvili....
A small study gave an oligopeptide called Prostamax to elderly people and found it changed some chromosome markers, suggesting it can loosen tightly packed DNA and possibly reactivate hidden genes, but the research didn’t show any direct health benefits or clear dosing guidance.
Kiladze. M M; Gorgoshidze. M M; Monaselidze. J J; Jokhadze. T T; Lezhava. T T
The study tested tiny amounts of copper, cadmium and the peptide prostamax on blood cells from older people and measured heat changes. It found that low‑level copper makes DNA more tightly packed, cadmium makes it looser and partially denatures, but neither metal changes the stability of cell proteins. The peptide’s effect wasn’t highlighted, so there’s no clear practical advice from this work.
Meskhi. T T; Khachidze. D D; Barbakadze. Sh Sh; Madzhagaladze. G G; Gorgoshidze....
The study looked at how a peptide called prostamax changes the way DNA-packaging proteins in human white blood cells melt when heated. It found tiny shifts in the temperatures at which certain DNA structures break down, suggesting very small changes in the way DNA is organized, but it did not link these changes to any health benefits or practical uses.