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Retatrutide

LY3437943, LY-3437943

Quick Stats
Studies 83
Trials 32
Completed PHASE2 INTERVENTIONAL NCT04881760

A Study of LY3437943 in Participants Who Have Obesity or Are Overweight

View on ClinicalTrials.gov Updated Dec 15, 2025

Brief Summary

This is a study of LY3437943 in participants who have obesity or are overweight. The main purpose is to learn more about how LY3437943 affects body weight loss. The study will last about 18 months and may include up to 18 visits.

Interventions

Name: LY3437943
Type: DRUG
Description: Administered SC
Name: Placebo
Type: DRUG
Description: Administered SC

Primary Outcomes

Measure: Mean Percent Change From Baseline in Body Weight
TimeFrame: Baseline, Week 24
Description: Least squares (LS) means were calculated using a mixed-effects model for repeated measures (MMRM) for post-baseline measures: Variable = Treatment\*Time + Baseline BMI (\< 36kg/m2 vs. \>=36 kg/m2)\*Time + Sex (Female vs. Male)\*Time + Baseline\*Time.

Trial Information

NCT ID

NCT04881760

Status

Completed

Study Type

INTERVENTIONAL

Phases

PHASE2

Sponsor

Eli Lilly and Company

Last Updated

December 15, 2025