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Retatrutide

LY3437943, LY-3437943

Quick Stats
Studies 83
Trials 32
Active Not Recruiting PHASE3 INTERVENTIONAL NCT06354660

Effect of Retatrutide Compared With Placebo in Adult Participants With Type 2 Diabetes and Inadequate Glycemic Control With Diet and Exercise Alone (TRANSCEND-T2D-1)

View on ClinicalTrials.gov Updated Dec 15, 2025

Brief Summary

The purpose of this study is to investigate the efficacy and safety of retatrutide compared with placebo in participants with Type 2 Diabetes and inadequate glycemic control. The study will last about 11 months and may include up to 11 visits.

Interventions

Name: Retatrutide
Type: DRUG
Description: Administered SC.
Name: Placebo
Type: DRUG
Description: Administered SC.

Primary Outcomes

Measure: Change from Baseline in Hemoglobin A1c (HbA1c) (%)
TimeFrame: Baseline, Week 40
Description:

Trial Information

NCT ID

NCT06354660

Status

Active Not Recruiting

Study Type

INTERVENTIONAL

Phases

PHASE3

Sponsor

Eli Lilly and Company

Last Updated

December 15, 2025