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Retatrutide

LY3437943, LY-3437943

Quick Stats
Studies 83
Trials 32
Active Not Recruiting PHASE3 INTERVENTIONAL NCT05882045

A Study of Retatrutide (LY3437943) in Participants With Obesity and Cardiovascular Disease

View on ClinicalTrials.gov Updated Dec 15, 2025

Brief Summary

The main purpose of this study is to evaluate the efficacy and safety of retatrutide once weekly in participants with obesity and established cardiovascular disease (CVD). The study will last about 113 weeks.

Interventions

Name: Retatrutide
Type: DRUG
Description: Administered SC
Name: Placebo
Type: DRUG
Description: Administered SC

Primary Outcomes

Measure: Percent Change from Baseline in Body Weight
TimeFrame: Baseline, Week 80
Description:

Trial Information

NCT ID

NCT05882045

Status

Active Not Recruiting

Study Type

INTERVENTIONAL

Phases

PHASE3

Sponsor

Eli Lilly and Company

Last Updated

December 15, 2025