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Retatrutide

LY3437943, LY-3437943

Quick Stats
Studies 83
Trials 32
Completed PHASE1 INTERVENTIONAL NCT03841630

A Safety Study of LY3437943 Given as a Single Injection in Healthy Participants

View on ClinicalTrials.gov Updated Dec 15, 2025

Brief Summary

This study is being conducted to determine the side effects related to LY3437943 given as a single injection under the skin to healthy participants. Blood tests will be performed to check how much LY3437943 gets into the bloodstream and how long the body takes to get rid of it. Each enrolled participant will receive a single dose of LY3437943 or placebo. The study will last up to approximately 71 days for each participant, including screening.

Interventions

Name: LY3437943
Type: DRUG
Description: Administered subcutaneously (SC)
Name: Placebo
Type: DRUG
Description: Administered SC

Primary Outcomes

Measure: Number of Participants with One or More Serious Adverse Event(s) (SAEs) Considered by the Investigator to be Related to Study Drug Administration
TimeFrame: Baseline through final follow-up at approximately Day 43
Description: A summary of SAEs and other non-serious adverse events (AEs), regardless of causality, will be reported in the Reported Adverse Events module

Trial Information

NCT ID

NCT03841630

Status

Completed

Study Type

INTERVENTIONAL

Phases

PHASE1

Sponsor

Eli Lilly and Company

Last Updated

December 15, 2025