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Retatrutide

LY3437943, LY-3437943

Quick Stats
Studies 83
Trials 32
Recruiting PHASE3 INTERVENTIONAL NCT07035093

A Study of Retatrutide (LY3437943) in Participants Who Have Obesity or Overweight and Chronic Low Back Pain

View on ClinicalTrials.gov Updated Dec 15, 2025

Brief Summary

The main purpose of this study is to evaluate the efficacy and safety of retatrutide in relieving chronic low back pain in participants who have obesity or overweight. Participation in the study will last about 80 weeks.

Interventions

Name: Retatrutide
Type: DRUG
Description: Administered SC
Name: Placebo
Type: DRUG
Description: Administered SC

Primary Outcomes

Measure: Change from Baseline in Pain Intensity Per Numeric Rating Scale
TimeFrame: Baseline, up to 72 weeks
Description:
Measure: Percent Change from Baseline in Body Weight
TimeFrame: Baseline, up to 72 weeks
Description:

Trial Information

NCT ID

NCT07035093

Status

Recruiting

Study Type

INTERVENTIONAL

Phases

PHASE3

Sponsor

Eli Lilly and Company

Last Updated

December 15, 2025