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Retatrutide

LY3437943, LY-3437943

Quick Stats
Studies 83
Trials 32
Completed PHASE1 INTERVENTIONAL NCT05548231

A Study of LY3437943 in Chinese Participants With Obesity Or Overweight

View on ClinicalTrials.gov Updated Dec 15, 2025

Brief Summary

The main purpose of this study is to learn about the safety and tolerability of LY3437943 when given to Chinese participants with overweight body mass index (BMI) or obesity. Blood tests will be performed to investigate how the body processes the study drug and how the study drug affects the body. Each enrolled participant will receive injections of LY3437943 or placebo given just under the skin. For each participant, the study will last about 20 weeks excluding screening period and may include up to 20 visits to the study center.

Interventions

Name: LY3437943
Type: DRUG
Description: Administered SC
Name: Placebo
Type: DRUG
Description: Administered SC

Primary Outcomes

Measure: Number of Participants with One or More Treatment Emergent Adverse Events (TEAEs) and Serious Adverse Event(s) (SAEs) Considered by the Investigator to be Related to Study Drug Administration
TimeFrame: Baseline through Week 20
Description: A summary of TEAEs, SAEs and other non-serious adverse events (AEs), regardless of causality, will be reported in the Reported Adverse Events module

Trial Information

NCT ID

NCT05548231

Status

Completed

Study Type

INTERVENTIONAL

Phases

PHASE1

Sponsor

Eli Lilly and Company

Last Updated

December 15, 2025