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Retatrutide

LY3437943, LY-3437943

Quick Stats
Studies 83
Trials 32
Completed PHASE1 INTERVENTIONAL NCT06003465

A Research Study Looking at Similarity Between LY3437943 Versions for Different Injection Devices

View on ClinicalTrials.gov Updated Dec 15, 2025

Brief Summary

The main purpose of this study is to look at the amount of the study drug, LY3437943, that gets into the blood stream and how long it takes the body to get rid of it when given using two different devices. The study will also evaluate the safety and tolerability of LY3437943 and information about any side effects experienced will be collected. For each participant, the total duration of the study will be approximately 16 weeks, including screening.

Interventions

Name: LY3437943
Type: DRUG
Description: Administered SC
Name: Test
Type: DEVICE
Description: Used to administer LY3437943 SC
Name: Reference
Type: DEVICE
Description: Used to administer LY3437943 SC

Primary Outcomes

Measure: Pharmacokinetics (PK): Maximum Concentration (Cmax) of LY3437943
TimeFrame: Predose up to 43 days postdose
Description: PK: Cmax of LY3437943
Measure: PK: Area Under the Plasma Concentration Versus Time Curve from Zero to T, Last Time Point (AUC[0-tlast]) of LY3437943
TimeFrame: Predose up to 43 days postdose
Description: PK: AUC\[0-tlast\] of LY3437943
Measure: PK: Area Under the Plasma Concentration Versus Time Curve From Zero to Infinity (AUC[0-∞]) of LY3437943
TimeFrame: Predose up to 43 days postdose
Description: PK: AUC(0-∞) of LY3437943

Trial Information

NCT ID

NCT06003465

Status

Completed

Study Type

INTERVENTIONAL

Phases

PHASE1

Sponsor

Eli Lilly and Company

Last Updated

December 15, 2025