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Semaglutide

Ozempic, Rybelsus, Wegovy

Quick Stats
Studies 78
Trials 100
Completed PHASE1 INTERVENTIONAL NCT06097390

A Research Study Looking at New Protein-based Tablets in Healthy Men - Oral Formulation III

View on ClinicalTrials.gov Updated Dec 15, 2025

Brief Summary

In this study, a known medicine called 'semaglutide' will be tested in two different tablet versions. The two tablets differ in the way these have been manufactured. The aim of the study is to investigate the amount of active ingredient in the blood after dosing the different tablet versions. Participants will receive one tablet version for 10 days (first treatment period) and the other version for 10 days (second treatment period). The treatment arm participants will be assigned to is decided by chance. The study will last for about 23 weeks for each participant. The study will enroll healthy male participants.

Interventions

Name: Semaglutide
Type: DRUG
Description: Oral administration

Primary Outcomes

Measure: Adjusted AUC0-24h,sema; adjusted area under the semaglutide plasma concentration-time curve
TimeFrame: From 0 to 24 hours after dosing on day 80 and 90
Description: Measured in hour\*nanomoles per liter (h\*nmol/L).

Trial Information

NCT ID

NCT06097390

Status

Completed

Study Type

INTERVENTIONAL

Phases

PHASE1

Sponsor

Novo Nordisk A/S

Last Updated

December 15, 2025