Completed
PHASE1
INTERVENTIONAL
NCT03010475
A Trial Investigating the Effect of Oral Semaglutide on the Pharmacokinetics of Furosemide and Rosuvastatin in Healthy Subjects
View on ClinicalTrials.gov
Updated Dec 15, 2025
Brief Summary
This trial is conducted in Europe. Tha aim of this trial is to investigate the effect of oral semaglutide on the pharmacokinetics of furosemide and rosuvastatin in healthy subjects.
Interventions
Name:
Furosemide
Type:
DRUG
Description:
Oral administration A total of three single doses.
Name:
Rosuvastatin
Type:
DRUG
Description:
Oral administration. A total of three single doses.
Name:
SNAC
Type:
DRUG
Description:
Oral administration. A total of five single doses.
Name:
Semaglutide
Type:
DRUG
Description:
Oral administration. Once daily.
Primary Outcomes
Measure:
Area under the furosemide plasma concentration-time curve
TimeFrame:
day 1, day 7, day 54
Description:
Based on sampling between 0 and 12 hours
Measure:
Area under the rosuvastatin plasma concentration-time curve
TimeFrame:
day 2, day 8, day 55
Description:
Based on sampling between 0 and 96 hours
Trial Information
NCT ID
NCT03010475
Status
Completed
Study Type
INTERVENTIONAL
Phases
PHASE1
Sponsor
Novo Nordisk A/S
Last Updated
December 15, 2025