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Semaglutide

Ozempic, Rybelsus, Wegovy

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Studies 78
Trials 100
Enrolling By Invitation OBSERVATIONAL NCT05503927

A Study to Evaluate the Safety of Exposure to Wegovy During Pregnancy

View on ClinicalTrials.gov Updated Dec 15, 2025

Brief Summary

This is an observational, retrospective, cohort study using administrative insurance claims data. The aim of this non-interventional study (NIS) is to compare maternal, fetal and infant outcomes of women exposed to Wegovy during pregnancy to a reference population not exposed to Wegovy, so that participants and healthcare providers can make informed treatment decisions.

Interventions

Name: No Intervention
Type: OTHER
Description: This is a non-interventional study, therefore no intervention is used.

Primary Outcomes

Measure: Number of Infants with Major Congenital Malformation (MCM)
TimeFrame: Birth up to 1 year of age
Description: Number of infants with MCM is defined as an abnormality of body structure or function that is present at birth, is of prenatal origin (that is, birth defect), has significant medical, social, or cosmetic consequences for the affected individual, and typically requires medical intervention.

Trial Information

NCT ID

NCT05503927

Status

Enrolling By Invitation

Study Type

OBSERVATIONAL

Sponsor

Novo Nordisk A/S

Last Updated

December 15, 2025