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Semaglutide

Ozempic, Rybelsus, Wegovy

Quick Stats
Studies 78
Trials 100
Not Yet Recruiting PHASE3 INTERVENTIONAL NCT07271251

A Research Study to See if Two Different Formulations of Oral Semaglutide Are Equally Safe and Effective in Reducing the Blood Sugar Level in Japanese People With Type 2 Diabetes

View on ClinicalTrials.gov Updated Dec 15, 2025

Brief Summary

The purpose of the study is to find out if the new tablet formulation oral semaglutide D is equally safe and effective as the approved oral semaglutide for treating Japanese people with type 2 diabetes. Participants will receive either oral semaglutide D (the treatment being tested) or oral semaglutide (the comparator); which treatment a participant gets is decided by chance. Oral semaglutide is an approved tablet (a treatment used as a comparator), while oral semaglutide D is described as the new tablet formulation being tested in this study. The study will last approximately 27 weeks.

Interventions

Name: Oral semaglutide
Type: DRUG
Description: Semaglutide will be administered orally once daily.

Primary Outcomes

Measure: Change in glycated haemoglobin (HbA1c).
TimeFrame: From baseline (week 0) to end of treatment (week 20)
Description: Measured in percentage (%)-point.

Trial Information

NCT ID

NCT07271251

Status

Not Yet Recruiting

Study Type

INTERVENTIONAL

Phases

PHASE3

Sponsor

Novo Nordisk A/S

Last Updated

December 15, 2025