Recruiting
PHASE2
INTERVENTIONAL
NCT06798207
A Clinical Trial of TQB2102 for Injection in Gynecological Tumors With Recurrent/Metastatic Advanced
View on ClinicalTrials.gov
Updated Dec 15, 2025
Brief Summary
TQB2102 is an antibody-drug conjugate comprised of a humanised antibody against Human Epidermal Growth Factor Receptor 2 (HER2), a enzyme-cleavable linker, and a topoisomerase I inhibitor payload, which combine the ability of antibodies to specifically target tumour cells with the highly potent killing activity of drugs with payloads too toxic for systemic administration. This is a Phase 2 study to evaluate the efficacy,and safety of TQB2102 for injection in recurrent/metastatic advanced gynecological tumors.
Interventions
Name:
TQB2102 for injection
Type:
DRUG
Description:
TQB2102 for injection is a HER2 dual-antibody-drug Conjugate (ADC).
Primary Outcomes
Measure:
Overall response rate (ORR)
TimeFrame:
Baseline up to 12 months
Description:
ORR defined as percentage of participants achieving complete response (CR) and partial response (PR)
Trial Information
NCT ID
NCT06798207
Status
Recruiting
Study Type
INTERVENTIONAL
Phases
PHASE2
Sponsor
Chia Tai Tianqing Pharmaceutical Group Nanjing Shunxin Pharmaceutical Co., Ltd.
Last Updated
December 15, 2025