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KE, L-Lys-L-Glu, lysylglutamic acid

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Studies 40
Trials 100
Recruiting PHASE2 INTERVENTIONAL NCT06798207

A Clinical Trial of TQB2102 for Injection in Gynecological Tumors With Recurrent/Metastatic Advanced

View on ClinicalTrials.gov Updated Dec 15, 2025

Brief Summary

TQB2102 is an antibody-drug conjugate comprised of a humanised antibody against Human Epidermal Growth Factor Receptor 2 (HER2), a enzyme-cleavable linker, and a topoisomerase I inhibitor payload, which combine the ability of antibodies to specifically target tumour cells with the highly potent killing activity of drugs with payloads too toxic for systemic administration. This is a Phase 2 study to evaluate the efficacy,and safety of TQB2102 for injection in recurrent/metastatic advanced gynecological tumors.

Interventions

Name: TQB2102 for injection
Type: DRUG
Description: TQB2102 for injection is a HER2 dual-antibody-drug Conjugate (ADC).

Primary Outcomes

Measure: Overall response rate (ORR)
TimeFrame: Baseline up to 12 months
Description: ORR defined as percentage of participants achieving complete response (CR) and partial response (PR)

Trial Information

NCT ID

NCT06798207

Status

Recruiting

Study Type

INTERVENTIONAL

Phases

PHASE2

Sponsor

Chia Tai Tianqing Pharmaceutical Group Nanjing Shunxin Pharmaceutical Co., Ltd.

Last Updated

December 15, 2025