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DSIP

Emideltide, DSIP nonapeptide, Delta sleep-inducing peptide

Quick Stats
Studies 458
Trials 82
Unknown NA INTERVENTIONAL NCT02799849

Metabolism Characteristics in the Children With Narcolepsy

View on ClinicalTrials.gov Updated Dec 15, 2025

Brief Summary

A significant weight gain and obesity are observed for most patients with narcolepsy, mainly at the beginning of the disease and narcolepsy in young children. There is no specific study on the population and the consequences of overweight in the lives of these long-term patients. Narcoleptic patients gain weight significantly at the onset of their illness. It is also known that weight gain is not related to the treatment of narcolepsy. The etiology of obesity in narcoleptic patients is not established. Several assumptions were made (physical activity, leptin diet, metabolism). The reason and the pathophysiology of overweight and obesity in this population therefore remain unclear. In this study, potential change in the total metabolism (24h) for narcoleptic children that could explain their tendency to obesity will be assessed ?

Interventions

Name: Sleep and metabolism assessment
Type: OTHER
Description:

Primary Outcomes

Measure: Determination of the metabolism at home
TimeFrame: 15 days
Description: Total energy expenditure in kilocalories per minute, including basal metabolic rate (MET) metabolism related to the activity (EEA), and physical activity (PA) measured by accelerometer (Actical) evaluated at home (15 days including scholar and non-scholar days).

Trial Information

NCT ID

NCT02799849

Status

Unknown

Study Type

INTERVENTIONAL

Phases

NA

Sponsor

Hospices Civils de Lyon

Last Updated

December 15, 2025