[Effect of deltaran on the mediatory balance in the brain of young and old rats with left-side laterality profile in case of carotid arteries occlusion].
Kim. T K TK; Karantysh. G V GV; Mendzheritskiĭ. A M AM; Ryzhak. G A GA
Key Findings
- Deltaran altered the distribution of neuromediators in the brains of old rats with left‑side brain dominance after carotid artery occlusion.
- The peptide showed an anti‑stress effect in these aged rats under hypoxic (low‑oxygen) conditions.
- Authors suggest Deltaran could be a neuroprotective agent and recommend further study.
Practical Outcomes
- For biohackers, there’s no actionable protocol yet—no human data, dosing, or safety profile. The finding is interesting but remains pre‑clinical, so it’s not ready for personal experimentation. More research is needed before considering any real‑world use.
Summary
A study in rats found that the peptide Deltaran (dsip) changed brain chemicals and reduced stress effects in older rats after blocking a carotid artery, hinting it might protect the brain under low‑oxygen conditions. However, the research was only in animals and didn’t give any dosing or safety info for people.
Abstract
The medico-social significance of ischemic brain lesions, which are the most frequent cause of disablement and death in older people, stipulates the need for efficient means of prevention and correction of central nervous system disorders in case of ischemic brain lesions. The efficacy of Deltaran in the correction of disordered neuromediator balance in the brain of rats of different age groups was studied on the model of carotid arteries occlusion. Studies showed, that Deltaran exerts an anti-stress effect on old rats with left-side profile by altering the neuromediators' distribution in animals' brain under conditions of hypoxia. This enables to recommend Deltaran for further study as a neuroprotector.
Study Information
pubmed
2007