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DSIP

Emideltide, DSIP nonapeptide, Delta sleep-inducing peptide

Quick Stats
Studies 458
Trials 82
2016 pubmed 4 citations

An RCT study on the feasibility of anterior transpedicular screw fixation in the cervicothoracic junction.

Zhao. Liujun L; Hong. Jinjiong J; Wandtke. Meghan E ME; Xu. Rongming R; Ma. Weihu W; Jiang. Weiyu W; Gu. Yongjie Y; Chen. Jianqing J; Wang. Liran L; Liu. Jiayong J; Ebraheim. Nabil A NA

Key Findings

  • The sideways angle of the pedicle gets smaller from C6 (about 47°) to T2 (about 21°).
  • The average distance from the screw entry point to the pedicle axis in the front‑back direction is about 7 mm.
  • Anterior transpedicular screws can be placed at C6, C7, and some T1 levels, but not reliably at T2.

Practical Outcomes

  • This study is about a surgical technique for spine stabilization and does not provide any actionable information for biohackers or self‑experimenters focused on longevity, metabolism, or performance. It has no direct relevance to peptide use or everyday health optimization protocols.

Summary

Researchers measured the angles and sizes of spinal bone pieces from C6 to T2 to see if a special front‑side screw can be safely placed there. They found the screw works at the lower neck (C6‑C7) and sometimes at T1, but it’s basically impossible to use this approach at T2.

Abstract

We evaluated the trajectory and the entry points of anterior transpedicular screws (ATPS) in the cervicothoracic junction (CTJ). This study aimed at investigating the feasibility of ATPS fixation in the CTJ. Application of an ATPS in the lower cervical spine has been reported; however, there were no reports exploring the feasibility of anterior transpedicular screw fixation in the CTJ. CT scans were performed in 50 cases and multiplanar reformation was used to measure the related parameters on pedicle axis view at C6-T2. Transverse pedicle angle, outer pedicle width, pedicle axis length, distance transverse intersection point (DtIP), sagittal pedicle angle, anterior vertebral body height, outer pedicle height, and distance sagittal intersection point (DsIP) were measured. The prozone of CTJ was divided into three different regions, which were named as the "manubrium region", the region "above" and "below" the manubrium. The distribution of the trajectory of sagittal pedicle axes was recorded in the three regions and the related data were statistically analyzed. There was no statistical difference in gender (P > 0.05). The transverse pedicle angle decreased from C6 (46.77° ± 2.72°) to T2 (20.62° ± 5.04°). DtIP increased from C6 to T2. DsIP was an average of 7.17 mm. The sagittal pedicle axis lines of the C6 and C7 were located in the region above the manubrium. T1 was mainly in the manubrium region followed by the region above the manubrium. T2 was mainly located in the manubrium region followed by the region below the manubrium. Implantation of ATPS at C6, C7, and some T1 is feasible through the low anterior cervical approach, while it is almost impossible to approach T2 that way.

Study Information

Provider

pubmed

Year

2016

Date

2016-03-01T00:00:00.000Z

DOI

10.1007/s00586-016-4470-z

Citations

4

References

28