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DSIP

Emideltide, DSIP nonapeptide, Delta sleep-inducing peptide

Quick Stats
Studies 458
Trials 82
1984 pubmed 2 citations

Cellular localization of binding sites for 3H-DSIP on neurones of cultured rat brain stem.

Hösli. E E; Schoenenberger. G A GA; Hösli. L L

Key Findings

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Practical Outcomes

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Summary

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Abstract

By means of light-microscopic autoradiography, binding sites for the delta sleep-inducing peptide (3H-DSIP) were observed on the soma and processes of cultured brain stem neurones but not on glial cells. Unlabelled DSIP at high concentrations inhibited binding of 3H-DSIP, indicating specific binding of this peptide. Our data suggest that brain stem neurones might possess receptors for the sleep-inducing peptide.

Study Information

Provider

pubmed

Year

1984

DOI

10.1159/000115710

Citations

2