One Case of Sudden Isolated Adrenocorticotropic Hormone (ACTH) Deficiency Diagnosed Based on Repeated Hypoglycemic Attacks.
Sato. Tomohide T
A 28‑year‑old man with Hashimoto's thyroiditis had repeated severe low‑blood‑sugar episodes caused by a sudden loss of ACTH, the hormone that tells the adrenal glands to make cortisol. Tests showed his pituitary was otherwise normal, and imaging showed small adrenal glands. He was treated with hydrocortisone and stopped having hypoglycemia. The case suggests that isolated ACTH deficiency, though rare, can cause dangerous low blood sugar and should be considered in similar situations.