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Hexarelin

Examorelin, HEX

Quick Stats
Studies 233
Trials 61
Completed NA INTERVENTIONAL NCT06678464

A Clinical Study to Assess the Safety and Effectiveness of Test Products in Healthy Adult Human Subjects With Dry and Sensitive Skin.

View on ClinicalTrials.gov Updated Dec 15, 2025

Brief Summary

An exploratory, prospective, open-label, randomized, three-arm, single-centre, safety, efficacy and in-use tolerability study of the three different test products in healthy adult human subjects with dry and sensitive skin. This exploratory, prospective, open-label, randomized, three-arm, single-centre, safety, efficacy and in-use tolerability study of the three different test products in healthy adult human subjects with dry and sensitive skin.

Detailed Description

A total of up to 84 (28 subjects/arm) healthy male and non-pregnant \| non-lactating female with equal distribution of dry and sensitive skin (1:1) with an age of 18-55 years will be enrolled to complete the 75 subjects (25 subjects/arm) the study. The potential subjects will be screened as per the inclusion \& exclusion criteria only after obtaining written informed consent from the subjects. Subjects will be pre-screened by the screening department of NovoBliss Research. Subjects will be called telephonically by the recruiting department prior to the enrolment visit. Subjects will be told during screening (prior to enrolment) not to wear any facial make-up on the study visit day. Visit 01 (Day 01): Screening, Enrolment, Baseline Evaluation, On Site Product Usage, Post Usage Evaluation * Visit 02 (Day 08 +2 Days): Evaluations, Product usage period * Visit 03 (Day 30 +2 Days): Product Usage Period, Evaluations * Visit 04 (Day 60 +2 Days): Evaluations, End of Study

Interventions

Name: Moiz MM
Type: OTHER
Description: Mode of Usage: After cleansing, apply liberally onto the skin and gently massage until fully absorbed. Manufactured By: Dermalogics Marketed By: Glowderma Lab Private Limited Frequency: Twice a Day Route of Administration: Topical
Name: Moiz XL
Type: OTHER
Description: Mode of Usage: After cleansing, apply liberally onto the skin and gently massage until fully absorbed. Manufactured By: Dermalogics Marketed By: Glowderma Lab Private Limited Frequency: Twice a Day Route of Administration: Topical
Name: Moiz LMF 48
Type: OTHER
Description: Mode of Usage: After cleansing, apply liberally onto the skin and gently massage until fully absorbed. Manufactured By: Dermalogics Marketed By: Glowderma Lab Private Limited Frequency: Twice a Day or as often as needed Route of Administration: Topical

Primary Outcomes

Measure: To evaluate the effectiveness of the test products in terms of change in skin hydration
TimeFrame: before usage of the test product on Day 01 and after usage of the test product at T20 mins on Day 01, Day 08 (+2 Days), Day 30 (+2 Days) and Day 60 (+2 Days)
Description: Instrumental evaluation by Corneometer CM 825
Measure: To assess the effectiveness of the test products in terms of change in DASI score
TimeFrame: before usage of the test product on Day 01 and after usage of the test product at T20 mins on Day 01, Day 08 (+2 Days), Day 30 (+2 Days) and Day 60 (+2 Days)
Description: Using DASI Score where 0 is absent 4 is extreme
Measure: To assess the effectiveness of the test products in terms of change in overall dry skin score (ODS)
TimeFrame: before usage of the test products on Day 01 and after usage of the test products at T20 mins on Day 01, Day 08 (+2 Days), Day 30 (+2 Days) and Day 60 (+2 Days)
Description: Using scoring scale where 0 is absent and 4 is extreme
Measure: To assess the effectiveness of the test products in terms of change in PGA score
TimeFrame: before usage of the test products on Day 01 and after usage of the test products at T20 mins on Day 01, Day 08 (+2 Days), Day 30 (+2 Days) and Day 60 (+2 Days)
Description: Scoring scale where 0 is none and 8 is extreme
Measure: To assess the effectiveness of test products in terms of change in skin barrier function
TimeFrame: before usage of the test products on Day 01 and after usage of the test products at T20 mins on Day 01, Day 08 (+2 Days), Day 30 (+2 Days) and Day 60 (+2 Days)
Description: Instrumental Evaluation by Tewameter TM Hex
Measure: To assess the effectiveness of the test products in terms of change in skin roughness
TimeFrame: before usage of the test products on Day 01 and after usage of the test products at T20 mins on Day 01, Day 08 (+2 Days), Day 30 (+2 Days) and Day 60 (+2 Days)
Description: Using Scoring Scale 0 is absent and 4 is extreme
Measure: To assess the effectiveness of the test products in terms of change in skin scaliness
TimeFrame: before usage of the test products on Day 01 and after usage of the test products at T20 mins on Day 01, Day 08 (+2 Days), Day 30 (+2 Days) and Day 60 (+2 Days)
Description: Using Scoring Scale 0 is absent and 4 is extreme
Measure: To assess the effectiveness of the test products in terms of change in skin smoothness
TimeFrame: before usage of the test products on Day 01 and after usage of the test products at T20 mins on Day 01, Day 08 (+2 Days), Day 30 (+2 Days) and Day 60 (+2 Days)
Description: Using Scoring Scale 0 is absent and 4 is extreme
Measure: To assess the effectiveness of the test products in terms of change in skin wrinkles
TimeFrame: before usage of the test products on Day 01 and after usage of the test products at T20 mins on Day 01, Day 08 (+2 Days), Day 30 (+2 Days) and Day 60 (+2 Days)
Description: Using Scoring Scale 0 is absent and 4 is extreme

Trial Information

NCT ID

NCT06678464

Status

Completed

Study Type

INTERVENTIONAL

Phases

NA

Sponsor

NovoBliss Research Pvt Ltd

Last Updated

December 15, 2025