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Hexarelin

Examorelin, HEX

Quick Stats
Studies 233
Trials 61
Not Yet Recruiting NA INTERVENTIONAL NCT06929988

A Clinical Study to Assess the Safety and Effectiveness of Test Product in Healthy Adult Human Subjects With Dry or Sensitive Skin

View on ClinicalTrials.gov Updated Dec 15, 2025

Brief Summary

This exploratory, prospective, open-label, single-centre, safety, efficacy and in-use tolerability study of the test product in healthy adult human subjects with dry or sensitive skin.

Detailed Description

A total of up to 32 healthy male and non-pregnant \| non-lactating female with dry or sensitive skin and an age of 18-55 years will be enrolled to complete the 30 subjects of the study. The potential subjects will be screened as per the inclusion \& exclusion criteria only after obtaining written informed consent from the subjects. Subjects will be pre-screened by the screening department of NovoBliss Research. Subjects will be called telephonically by the recruiting department prior to the enrollment visit. Subjects will be told during screening (prior to enrolment) not to wear any facial make-up on the study visit day. The adult female subjects will be instructed to visit the facility as per the below visits. Visit 01 (Day 01): Screening, Enrolment, Baseline Evaluation, On Site Product Usage, Post Usage Evaluation Visit 02 (Day 02): Evaluations, Product usage period Visit 03 (Day 15 +2 Days): Evaluations, End of the Study

Interventions

Name: Creanz Lotion
Type: OTHER
Description: Mode of Usage: Apply sufficient quantity of Creanz Nourishing Body lotion to face and body for smooth and moisturised skin. Frequency: Twice a Day Route of Administration: Topical

Primary Outcomes

Measure: Change in skin hydration
TimeFrame: baseline before usage of the test product on Day 01 and after usage of the test product at T20 mins on Day 01, Day 02, and Day 15 (+2 Days)
Description: Instrumental Assessment: Corneometer CM 825
Measure: Change in skin elasticity
TimeFrame: Baseline before usage of the test product on Day 01 and after usage of the test product at T20 mins on Day 01, Day 02, and Day 15 (+2 Days)
Description: Instrumental Assessment: Cutometer Dual MPA 580
Measure: Change in Dry skin area and severity index
TimeFrame: Baseline before usage of the test product on Day 01 and after usage of the test product at T20 mins on Day 01, Day 02, and Day 15 (+2 Days)
Description: Dermatological assessment: 0 = Absent; 4 = Severe
Measure: Change in Overall Dry skin Score
TimeFrame: Baseline before usage of the test product on Day 01 and after usage of the test product at T20 mins on Day 01, Day 02, and Day 15 (+2 Days)
Description: Dermatological assessment: 0 = Absent; 4 = Dominated by large scales
Measure: Change in skin barrier function
TimeFrame: Baseline before usage of the test product on Day 01 and after usage of the test product at T20 mins on Day 01, Day 02, and Day 15 (+2 Days)
Description: Instrumental Assessment: TEWAMeter TM Hex
Measure: Change in skin roughness
TimeFrame: Baseline before usage of the test product on Day 01 and after usage of the test product at T20 mins on Day 01, Day 02, and Day 15 (+2 Days)
Description: Instrumental Assessment: VISIOSCAN VC 20 Plus
Measure: Change in skin scaliness
TimeFrame: Baseline before usage of the test product on Day 01 and after usage of the test product at T20 mins on Day 01, Day 02, and Day 15 (+2 Days)
Description: Instrumental Assessment: VISIOSCAN VC 20 Plus
Measure: Change in skin smoothness
TimeFrame: Baseline before usage of the test product on Day 01 and after usage of the test product at T20 mins on Day 01, Day 02, and Day 15 (+2 Days)
Description: Instrumental Assessment: VISIOSCAN VC 20 Plus
Measure: Change in skin wrinkles
TimeFrame: Baseline before usage of the test product on Day 01 and after usage of the test product at T20 mins on Day 01, Day 02, and Day 15 (+2 Days)
Description: Instrumental Assessment: VISIOSCAN VC 20 Plus

Trial Information

NCT ID

NCT06929988

Status

Not Yet Recruiting

Study Type

INTERVENTIONAL

Phases

NA

Sponsor

SAVA Healthcare Limited

Last Updated

December 15, 2025