Completed
NA
INTERVENTIONAL
NCT06379516
Process Validation in Dermatology: Assessing Wound Creation Methods and Treatment Efficacy
View on ClinicalTrials.gov
Updated Dec 15, 2025
Brief Summary
The primary objective of this study is to validate controlled methods of wound, including 1%w/v SLS, 3%w/v SLS, and 24-24 times tape stripping, on the forearms of subjects. The study aims to standardize the procedures for creating wounds and systematically evaluate the effects of these methods on various skin parameters.
Interventions
Name:
Moisturising Cream (5%)
Type:
OTHER
Description:
This intervention is a moisturiging cream of concentration 5% for topical application to the respective test sites.
Name:
Moisturising Cream (10%)
Type:
OTHER
Description:
This intervention is a moisturiging cream of concentration 10% for topical application to the respective test sites.
Name:
Coconut Oil
Type:
OTHER
Description:
This intervention is a 100% pure coconut oil product (Parachute Pure Coconut Oil) for topical application to the respective test sites.
Primary Outcomes
Measure:
Trans Epidermal Water Loss (TEWL)
TimeFrame:
Days -02, -01, 01, 02, 05, 08, 28
Description:
Using the Tewameter® TM Hex
Measure:
Skin hydration
TimeFrame:
Days -02, -01, 01, 02, 05, 08, 28
Description:
Using the Corneometer® CM 825
Measure:
Skin surface topography
TimeFrame:
Days -02, -01, 01, 02, 05, 08, 28
Description:
Assessment of skin smoothness, scaliness, roughness, wrinkles using the Visioscan® VC 20plus.
Trial Information
NCT ID
NCT06379516
Status
Completed
Study Type
INTERVENTIONAL
Phases
NA
Sponsor
NovoBliss Research Pvt Ltd
Last Updated
December 15, 2025