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Hexarelin

Examorelin, HEX

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Studies 233
Trials 61
Completed NA INTERVENTIONAL NCT06178796

Bone-Implant Contact Surface Influence on Dental Implant Stability

View on ClinicalTrials.gov Updated Dec 15, 2025

Brief Summary

This study aims to evaluate the changes in the stability and bone-implant contact surface of implants of the same macro-design placed with particle grafting in the fresh extraction socket, without grafting, and placed in healed implant sites.

Interventions

Name: Dental implant
Type: DEVICE
Description: Dental implant placement

Primary Outcomes

Measure: Change in Implant Stability Quotient (ISQ) values
TimeFrame: 12 weeks
Description: Implant Stability Quotient (ISQ) is a scale from 1 to 100, to quantify implant stability in bone (higher values mean higher stability). ISQ numerical values are generated by applying resonance frequency analysis (RFA) or sound waves through a specialized peg attached to the implant. Data were combined to reduce the number of intervals for analysis purposes. Data from intervals were combined as follows: T0: baseline T1: follow-up of eight weeks T2: follow-up of twelve weeks
Measure: Change in bone-implant contact surface
TimeFrame: 12 weeks
Description: The tooth slated for extraction will be segmented from the preoperative CBCT data, followed by a virtual tooth extraction process. For each patient, intraoral surface scanning with the scanbodies in place will be conducted using an intraoral scanner. This datas will be overlaid onto the postoperative intraoral scan image. The area where the implant surface made contact with the extracted tooth surface will be identified as the surface without implant bone contact (BINC), while the remaining area will be designated the bone implant contact (BIC) surface. By subtracting the sum of the BINC and BIC from the entire implant surface, the implant surface facing the gap space (IGS) and its corresponding area on the BINC side will obtain. To isolate the BIC surface for measurement, the sum of the BINC and BIC from the sum of the BINC and IGS will subtracted. This result will then be added to the total implant surface measurement, divided by two, allowing for the measurement of the BIC surface.
Measure: Primary insertion torque value
TimeFrame: 1 day At the implant placement
Description: The torque value was recorded as insertion torque value of this case at the moment when the implant positioned at the 1mm under the socket wall edge and correct hex position. It gives numerical values from 0 to 100 (higher values mean higher stability).

Trial Information

NCT ID

NCT06178796

Status

Completed

Study Type

INTERVENTIONAL

Phases

NA

Sponsor

Marmara University

Last Updated

December 15, 2025