HGH Fragment 176-191

hGH 176-191, Frag 176-191, Growth Hormone Fragment 176-191

A synthetic peptide derived from human growth hormone that promotes fat loss by stimulating lipolysis and inhibiting lipogenesis without growth effects.

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Studies 2

Trials 1

Formula C₇₈H₁₂₃N₂₃O₂₃S₂

Overview Studies 2 Clinical Trials 1

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pubmed 1978

Hyperglycemic action of synthetic C-terminal fragments of human growth hormone.

Ng. F M FM; Bornstein. J J

In rats, short pieces of human growth hormone that include the 176‑191 region cause a quick spike in blood sugar and a longer increase in insulin, and they make the animals less sensitive to insulin. Two nearby fragments (179‑191 and 180‑191) did nothing. The effect only shows up when the peptide has the right sequence and shape.

Utility 1

pubmed Jun 27, 2022

Human Growth Hormone Fragment 176-191 Peptide Enhances the Toxicity of Doxorubicin-Loaded Chitosan Nanoparticles Against MCF-7 Breast Cancer Cells.

Habibullah. Mahmoud M MM; Mohan. Syam S; Syed. Nabeel Kashan NK; Makeen. Hafiz A HA; Jamal. Qazi Moh...

Scientists packed a short piece of human growth hormone (the 176‑191 fragment) together with the chemotherapy drug doxorubicin inside tiny chitosan particles. In lab tests on breast cancer cells, this combo killed more cancer cells than doxorubicin alone, likely because the peptide helped the drug stick better to cancer‑related proteins.