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IGF-1

Insulin-like Growth Factor 1, Somatomedin C

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Studies 92
Trials 100
Withdrawn OBSERVATIONAL NCT01470430

VEGF In Systemic Circulation Of ROP-infants

View on ClinicalTrials.gov Updated Dec 15, 2025

Brief Summary

The purpose of this study is to measure systemic levels of vascular endothelial growth factor (VEGF) and other proteins (e.g. IGF-1) in the systemic circulation of infants with retinopathy of prematurity (ROP) following ocular treatment with either intravitreal injections of anti-VEGF agents or retinal laser photocoagulation. The primary aim is to determine if serum VEGF levels change after treatment.

Primary Outcomes

Measure: Systemic VEGF levels following treatment
TimeFrame: 16 weeks
Description: comparing VEGF levels in serum of ROP infants treated with intravitreal anti-VEGF agents vs. retinal laser photocoagulation over 16 weeks post treatment

Trial Information

NCT ID

NCT01470430

Status

Withdrawn

Study Type

OBSERVATIONAL

Sponsor

University Hospital Freiburg

Last Updated

December 15, 2025