Completed
NA
INTERVENTIONAL
NCT00533065
Effects of Donepezil on Deficits Associated With Age-Related Decrease of Growth Hormone
View on ClinicalTrials.gov
Updated Dec 15, 2025
Brief Summary
The planned study has two purposes: 1. It is to provide evidence that the administration of a cholinesterase inhibitor will result in an increase of IGF-I (primary variable) and in an increase of the secretion growth hormone (secondary variable) that can be maintained throughout the treatment-period of one year. 2. The study also tests the hypothesis that maintenance of increased blood levels of growth hormone and IGF-I can stop or delay the age-related changes of body composition (secondary variables) .
Interventions
Name:
Donepezil
Type:
DRUG
Description:
week1 - week12: 1 tablet per day (5mg) week13 - week52: 1 tablet per day (10mg)
Primary Outcomes
Measure:
Serum IGF1
TimeFrame:
one year
Description:
Trial Information
NCT ID
NCT00533065
Status
Completed
Study Type
INTERVENTIONAL
Phases
NA
Sponsor
Ludwig Boltzmann Gesellschaft
Last Updated
December 15, 2025