Menu
Peptide Database
Results
No peptides found
Featured

Use search to browse all 100+ peptides

Kisspeptin-10

KP-10, Metastin (45-54), Kisspeptin-10 (human), KiSS-1

Quick Stats
Studies 877
Trials 47
Not Yet Recruiting PHASE1 INTERVENTIONAL NCT07224490

Kisspeptin to Quantify GnRH Neuronal Function in Health and Disease

View on ClinicalTrials.gov Updated Dec 15, 2025

Brief Summary

The objective of this protocol is to use a case-control paradigm to compare the response to an intravenous administration of kisspeptin in individuals with and without post-covid-19 syndrome. The study subjects will receive a single bolus of kisspeptin. This study will utilize the technique of frequent blood sampling (q10 minutes) to provide detailed neuroendocrine characterization of endogenous LH secretion before and after kisspeptin administration. This frequency of blood sampling is required to define the features of LH pulses.

Detailed Description

Delivery of Interventions: * 1-2 hours of q10 minute blood sampling * Administration of a single kisspeptin bolus in a dosing range of 0.313 - 13.19 μg/kg

Interventions

Name: Kisspeptin 112-121
Type: DRUG
Description: Single bolus of kisspeptin

Primary Outcomes

Measure: Difference in mean luteinizing hormone (LH) amplitude between cases and controls
TimeFrame: Day of study visit (one to two hours)
Description: Difference between cases and controls of mean LH amplitude in response to kisspeptin

Trial Information

NCT ID

NCT07224490

Status

Not Yet Recruiting

Study Type

INTERVENTIONAL

Phases

PHASE1

Sponsor

Stephanie B. Seminara, MD

Last Updated

December 15, 2025