Completed
OBSERVATIONAL
NCT04012632
Kisspeptin/GPR54 Pathway and Early Puberty
View on ClinicalTrials.gov
Updated Dec 15, 2025
Brief Summary
There was a worldwide early trend in girls'age for puberty onset. The timing of puberty onset varies greatly among individuals, and much of this variation is modulated by genetic factors. This study was designed to explored the association of polymorphisms in KISS1/GPR54 pathway genes and the risk of early puberty in Chinese Han girls.
Interventions
Name:
this study was an observational study and no interventions were given to the participants
Type:
OTHER
Description:
the participants were recruited and the data as well as blood sample were collected.
Primary Outcomes
Measure:
the polymorphism in the KISS1/GPR54 pathway genes
TimeFrame:
3 months
Description:
functional SNP loci of the KISS1/GPR54 pathway genes KISS1, KISSIR, PLCB1, PRKCA, and ITPR1 were selected and detected.
Trial Information
NCT ID
NCT04012632
Status
Completed
Study Type
OBSERVATIONAL
Sponsor
Shenzhen Center for Disease Control and Prevention
Last Updated
December 15, 2025