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KPV

Lys-Pro-Val, α-MSH (11-13)

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Studies 104
Trials 57
Completed OBSERVATIONAL NCT02154815

Pre-emptive Kidney Transplantation Quality of Life

View on ClinicalTrials.gov Updated Dec 15, 2025

Brief Summary

The main objective is to assess the psychological impact of pre-emptive kidney transplantation on patients' quality of life taking into account psychological adjustment (response shift), compared to patients who have experienced a short pre-transplant dialysis period of less than 36 months.

Detailed Description

The following outcomes will also be compared between Patients with Pre-emptive Transplantation and Patients with Dialysis before Transplantation : a) changes in quality of life, subjective well-being, perceived anxiety and depressive disorders as well as perceived stress during follow-up taking into account psychological adjustment (response shift) ; b) The coping strategies (process of managing stressful circumstances) and post-traumatic growth (positive psychological change experienced as a result of the struggle with highly challenging life circumstances) ; c) The 2-year post transplantation graft survival and patient outcomes: evolution of the Graft Filtration Rate, the proteinuria level ; d) The Kidney Transplant Failure Score (KTFS, patent N°0959043) at one year post transplantation ; e) The post-transplantation time to return to work and patients compliance to treatment.

Interventions

Name: Questionnaires : Patient-Reported Outcomes
Type: OTHER
Description: Patient-Reported Outcomes completion every six months prior to surgery, at hospital discharge, and at 3, 6,12, 24, 36, 48, 72 months

Primary Outcomes

Measure: Change in quality of life
TimeFrame: through study completion, an average of 5 years
Description: The change in quality of life, taking into account psychological adjustment of the patient (response shift). This criterion will be measured by a specifically developed questionnaire : ReTransQol

Trial Information

NCT ID

NCT02154815

Status

Completed

Study Type

OBSERVATIONAL

Sponsor

Nantes University Hospital

Last Updated

December 15, 2025