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KPV

Lys-Pro-Val, α-MSH (11-13)

Quick Stats
Studies 104
Trials 57
2017 pubmed 81 citations

Current clinical nutrition practices in critically ill patients in Latin America: a multinational observational study.

Vallejo. Karin Papapietro KP; Martínez. Carolina Méndez CM; Matos Adames. Alfredo A AA; Fuchs-Tarlovsky. Vanessa V; Nogales. Guillermo Carlos Contreras GCC; Paz. Roger Enrique Riofrio RER; Perman. Mario Ignacio MI; Correia. Maria Isabel Toulson Davisson MITD; Waitzberg. Dan Linetzky DL

Key Findings

  • ~74% of ICU patients were malnourished
  • Only about 60% met >90% of calorie targets
  • Combining enteral and parenteral nutrition increased odds of meeting calorie/protein goals (OR 1.56)

Practical Outcomes

  • For self‑experimenters, the paper shows that supplementing enteral feeding with parenteral nutrition can improve energy delivery in critically ill patients, but the findings are specific to hospital ICU protocols and not directly transferable to personal nutrition regimens.

Summary

The study examined ICU nutrition in Latin America, finding most patients were malnourished and many didn’t reach calorie goals, especially when only tube feeding was used. Adding IV nutrition helped meet calorie and protein targets, but it’s rarely used.

Abstract

Malnutrition in critically ill adults in the intensive care unit (ICU) is associated with a significantly elevated risk of mortality. Adequate nutrition therapy is crucial to optimise outcomes. Currently, there is a paucity of such data in Latin America. Our aims were to characterise current clinical nutrition practices in the ICU setting in Latin America and evaluate whether current practices meet caloric and protein requirements in critically ill patients receiving nutrition therapy. We conducted a cross-sectional, retrospective, observational study in eight Latin American countries (Argentina, Brazil, Chile, Colombia, Ecuador, Mexico, Panama, and Peru). Eligible patients were critically ill adults hospitalised in the ICU and receiving enteral nutrition (EN) and/or parenteral nutrition (PN) on the Screening Day and the previous day (day -1). Caloric and protein balance on day -1, nutritional status, and prescribed nutrition therapy were recorded. Multivariable logistic regression analysis was performed to identify independent predictors of reaching daily caloric and protein targets. The analysis included 1053 patients from 116 hospitals. Evaluation of nutritional status showed that 74.1% of patients had suspected/moderate or severe malnutrition according to the Subjective Global Assessment. Prescribed nutrition therapy included EN alone (79.9%), PN alone (9.4%), and EN + PN (10.7%). Caloric intake met >90% of the daily target in 59.7% of patients on day -1; a caloric deficit was present in 40.3%, with a mean (±SD) daily caloric deficit of -688.8 ± 455.2 kcal. Multivariable logistic regression analysis showed that combined administration of EN + PN was associated with a statistically significant increase in the probability of meeting >90% of daily caloric and protein targets compared with EN alone (odds ratio, 1.56; 95% confidence interval, 1.02-2.39; p = 0.038). In the ICU setting in Latin America, malnutrition was highly prevalent and caloric intake failed to meet targeted energy delivery in 40% of critically ill adults receiving nutrition therapy. Supplemental administration of PN was associated with improved energy and protein delivery; however, PN use was low. Collectively, these findings suggest an opportunity for more effective utilisation of supplemental PN in critically ill adults who fail to receive adequate nutrition from EN alone.

Study Information

Provider

pubmed

Year

2017

Date

2017-08-25T00:00:00.000Z

DOI

10.1186/s13054-017-1805-z

Citations

81

References

39