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Rigin, Pal-GQPR, Palmitoyl-Gly-Gln-Pro-Arg
A synthetic palmitoylated tetrapeptide used in cosmetics to suppress inflammation, stimulate collagen production, and enhance skin repair for anti-aging benefits.
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Topical
1-10 ppm
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How It Works: Palmitoyl Tetrapeptide-7 acts as an anti-inflammatory agent in the skin by inhibiting key cytokines, thereby preserving the extracellular matrix and promoting regeneration.
Xing. Cencan C; Hou. Liangxuan L; Sun. Chunbin C; Chen. Hongyu H; Li. Yingxian Y...
Scientists made a gel that mixes a skin‑friendly peptide (Pal‑7) with chitosan and stem cells from baby teeth. When they put this gel on wounds in diabetic mice, the cuts healed faster, with less inflammation and more new blood vessels.
Resende. Diana I S P DISP; Ferreira. Marta Salvador MS; Sousa-Lobo. José Ma...
The study looked at 88 facial products for sensitive skin and found that only about 17% contain peptides, including palmitoyl‑tetrapeptide‑7. There’s very little solid clinical proof that these peptides help sensitive skin – most of the data comes from patents and company brochures, and only one small trial actually tested people with sensitive skin.
Mondon. Philippe P; Hillion. Mélanie M; Peschard. Olivier O; Andre. Nada N;...
The study shows that a skin‑care blend containing palmitoyl tetrapeptide‑7 (along with another peptide) can improve the structure of the skin’s extracellular matrix and make the skin‑dermis junction smoother in older skin. The researchers used advanced imaging tools to see these changes, and they found that the peptide blend reduced a low‑echogenic band under the skin, which is a sign of healthier tissue.