Score
3
2007
pubmed
4 citations
Selank and its metabolites maintain homeostasis in the gastric mucosa.
Pavlov. T S TS; Samonina. G E GE; Bakaeva. Z V ZV; Zolotarev. Yu A YA; Guseva. A A AA
Key Findings
- Selank reduced the size of experimentally induced gastric ulcers in three different models
- Metabolites formed from Selank in the body also showed anti‑ulcer effects
- The peptide and its metabolites appear to help keep the stomach lining stable
Practical Outcomes
- Selank may offer extra gut‑protective benefits for those interested in stomach health, but the evidence is from animal studies only. Until human data are available, it should be used cautiously and not as a primary ulcer treatment.
Summary
A study found that Selank, a synthetic peptide usually used for anxiety, also helped protect the stomach lining in animal tests, making ulcers smaller.
Abstract
Antiulcer properties of a synthetic anxiolytic Selank and in vivo formed metabolites of this compound were studied on 3 experimental models of ulceration. The test peptides decreased the area of experimental gastric ulcers.
Study Information
Provider
pubmed
Year
2007
DOI
10.1007/s10517-007-0014-1
Citations
4
References
2