Syntheses, Reactivities, Characterization, and Crystal Structures of Dipalladium Complexes Containing the 1,3-pyrimidinyl Ligand: Structures of [Pd(PPh<sub>3</sub>)(Br)]<sub>2</sub>(μ,η<sup>2</sup>-C<sub>4</sub>H<sub>3</sub>N<sub>2</sub>)<sub>2</sub>, [Pd(Br)]<sub>2</sub>(μ,η<sup>2</sup>-Hdppa)<sub>2</sub>, and [{Pd(PPh<sub>3</sub>)(CH<sub>3</sub>CN)}<sub>2</sub>(μ,η<sup>2</sup>-C<sub>4</sub>H<sub>3</sub>N<sub>2</sub>)<sub>2</sub>][BF<sub>4</sub>]<sub>2</sub>.
Wang. Hsiao-Fen HF; Yih. Kuang-Hway KH; Lee. Gene-Hsiang GH
Key Findings
- Synthesized multiple dipalladium complexes with pyrimidinyl ligands
- Determined crystal structures of three complexes using X‑ray diffraction
- Showed ligand exchange reactions and formation of bridged palladium species
Practical Outcomes
- The findings are purely chemical and have no direct implications for longevity, metabolism, body composition, or performance protocols used by biohackers.
Summary
The paper describes how scientists made and studied several new palladium‑based chemical compounds, focusing on their synthesis, structure, and crystal analysis, but it does not discuss selank or any health‑related effects.
Abstract
In a refluxing chloroform solution<b>,</b> the η<sup>1</sup>-pyrimidinyl {pyrimidinyl = C<sub>4</sub>H<sub>3</sub>N<sub>2</sub>} palladium complex [Pd(PPh<sub>3</sub>)<sub>2</sub>(η<sup>1</sup>-C<sub>4</sub>H<sub>3</sub>N<sub>2</sub>)(Br)], <b>1</b> exhibited intermolecular displacement of two triphenylphosphine ligands to form the doubly bridged η<sup>2</sup>-pyrimidinyl Dipalladium complex [Pd(PPh<sub>3</sub>)(Br)]<sub>2</sub>(μ,η<sup>2</sup>-C<sub>4</sub>H<sub>3</sub>N<sub>2</sub>)<sub>2</sub>, <b>3</b>. The treatment of <b>1</b> with Hdppa {Hdppa = <i>N</i>,<i>N</i>-bisdiphenyl phosphinoamine} in refluxing dichloromethane yielded the doubly bridged Hdppa dipalladium complex [Pd(Br)]<sub>2</sub>(μ,η<sup>2</sup>-Hdppa)<sub>2</sub>, <b>4</b>. Complex <b>1</b> reacted with the bidentate ligand, NH<sub>4</sub>S<sub>2</sub>CNC<sub>4</sub>H<sub>8</sub> and, NaS<sub>2</sub>COEt, and the tridentate ligand, KTp {Tp = tris(pyrazoyl-1-yl)borate}, to form the η<sup>2</sup>-dithio η<sup>1</sup>-pyrimidinyl complex [Pd(PPh<sub>3</sub>)(η<sup>1</sup>-C<sub>4</sub>H<sub>3</sub>N<sub>2</sub>)(η<sup>2</sup>-SS)], (<b>5</b>: SS = S<sub>2</sub>CNC<sub>4</sub>H<sub>8</sub>; <b>6</b>: SS = S<sub>2</sub>COEt) and η<sup>2</sup>-Tp η<sup>1</sup>-pyrimidinyl complex [Pd(PPh<sub>3</sub>)(η<sup>1</sup>-C<sub>4</sub>H<sub>3</sub>N<sub>2</sub>)(η<sup>2</sup>-Tp)], <b>7</b>, respectively. Treatment of <b>1</b> with AgBF<sub>4</sub> in acetonitrile at room temperature resulted in the formation of the doubly bridged η<sup>2</sup>-pyrimidinyl dipalladium complex [{Pd(PPh<sub>3</sub>)(CH<sub>3</sub>CN)}<sub>2</sub>(μ,η<sup>2</sup>-C<sub>4</sub>H<sub>3</sub>N<sub>2</sub>)<sub>2</sub>][BF<sub>4</sub>]<sub>2</sub>, <b>8</b>. All of the complexes were identified using spectroscopic methods, and complexes <b>3</b>, <b>4</b>, and <b>8</b> were determined using single-crystal X-ray diffraction analyses.
Study Information
pubmed
2020
2020-04-27T00:00:00.000Z
10.3390/molecules25092035
17