[The results of the application of the pre-formed physical factors and neuroprotective therapy for the rehabilitative treatment of the patients with diabetic retinopathy].
Nazarova. G A GA; Konchugova. T V TV; Iurova. O V OV; Turova. E A EA; Rassulova. M A MA; Sichinava. N V NV; Morozova. N E NE
Key Findings
- Endonasal electrophoresis of 0.1% semax improved visual, perimetric, and electrophysiological measures in diabetic retinopathy patients
- The benefit was strongest and lasted up to 12 months in the electrophoresis group
- Intranasal drops of semax were less effective than the electrophoresis method
Practical Outcomes
- For most biohackers, this isn’t a directly useful protocol unless you have diabetic eye disease and access to electrophoresis equipment. It suggests semax might have neuro‑protective eye benefits, but the delivery method is specialized and not ready for general longevity or performance use.
Summary
A study on 114 people with early-stage diabetic eye disease found that delivering the brain‑active peptide semax through a special nose‑based electric method improved vision tests and lasted up to a year, better than regular nasal drops or just standard diabetes meds.
Abstract
To evaluate the effectiveness of the neuroprotective agent used to treat the patients presenting with non-proliferative diabetic retinopathy. The study included 114 patients (228 eyes) at the age varying from 42 to 70 who presented with diabetes mellitus and non-proliferative diabetic retinopathy. Three groups were formed depending on the mode of treatment. The patients in main group underwent endonasal electrophoresis of 0.1% semax preparation. Patients of the comparison group were treated with intranasal instillations of semax and those of the control group received only standard hypoglycemic therapy and treatment with Doxy-Hem. The patients of the first two groups showed positive dynamics of the studied functional characteristics (visual, perimetric, and electrophysiological ones). The most pronounced and long-standing (up to 12 months) positive effect on the visual function was documented in the main group. The results of the present study give reason to recommend the inclusion of endonasal electrophoresis in the combined rehabilitation treatment of the patients presenting with diabetes mellitus and non-proliferative diabetic retinopathy.
Study Information
pubmed
2013