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Semax

ACTH(4-10) analogue, Heptapeptide SEMAX

Quick Stats
Studies 172
Trials 37
Score 2
2010 pubmed

[Effect of adrenocorticotropic hormone (ACTH4-10) on information network of the cardiovascular systems].

Dmitrieva. N V NV; Lonskaia. L F LF; Bakaneva. V F VF

Key Findings

  • ACTH4-10 (a semax‑like peptide) alters cardiovascular adaptation patterns in young adults
  • Health status improved in subjects with moderately active physiology and reduced vascular tone
  • Changes were detected using EGG, rheovasogram, and respiration rate measurements

Practical Outcomes

  • Semax may have modest benefits for regulating vascular tone and stress‑related cardiovascular responses, but the evidence is limited to a small student group and lacks dosing details, so it’s not ready for a concrete protocol for longevity or performance optimization.

Summary

The study tested a short fragment of ACTH (similar to the peptide semax) in students and found it can shift how their cardiovascular system adapts, especially helping those with moderate activity levels and low blood‑vessel tone, leading to overall better health markers.

Abstract

The polyparametric description of adaptation syndromes in students using a uniform set of parameters of cardiovascular system and their relationships is presented. An analog of adrenocorticotropic hormone (ACTH4-10) is shown to exert varying effects on the development of different adaptation syndromes. Adaptation syndromes characterized by moderately active physiological processes (as judged by EGG, rheovasogram, respiration rate) and lowered vascular tonus were associated with marked improvement of the health status.

Study Information

Provider

pubmed

Year

2010