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TB-500

Thymosin Beta-4, TB4, Tβ4

Quick Stats
Studies 6
Trials 21
Completed NA INTERVENTIONAL NCT04745897

Accessibility of the World Health Organization's eTB Catalogue of Recommendations

View on ClinicalTrials.gov Updated Dec 15, 2025

Brief Summary

The World Health Organization's Global Tuberculosis Programme (WHO-GTB) issues evidence-informed guideline recommendations on tuberculosis (TB). These recommendations are used by decision-makers, guideline developers and other stakeholders. In an effort to improve the accessibility and usability of these recommendations, a new eTB catalogue of recommendations has been developed. This study aims to compare the accessibility of the new eTB catalogue to the earlier method of accessing recommendations directed through the general WHO website.

Detailed Description

This is a two-arm superiority randomized controlled trial. The primary objective is to compare the accessibility of information between the eTB catalogue (intervention) and WHO TB (comparison). Secondary outcomes include understanding of the information, satisfaction of catalogue presentation, and preference toward the catalogue. Current and potential users of TB recommendations will be recruited. Data will be collected using a survey with demographic questions and subsequent 1:1 randomization to the intervention. Superiority will be declared if the mean difference in accessibility is 0.5 or greater for the intervention arm on the seven-point Likert scale.

Interventions

Name: eTB Catalogue of Recommendations (eTB)
Type: OTHER
Description: eTB Catalogue of Recommendations (eTB)
Name: World Health Organization Tuberculosis Website (WHO TB)
Type: OTHER
Description: World Health Organization Tuberculosis Website (WHO TB)

Primary Outcomes

Measure: Accessibility of Information on a Seven-Point Likert Scale
TimeFrame: Duration of survey (approximately 10 minutes)
Description: The primary outcome is the accessibility of information on the eTB catalogue compared to the current WHO TB guidelines. Accessibility is defined as the ability to access and use information. This outcome considers the four following domains: (1) how easy is it to find the information (2) how easy is it to understand the information (3) whether the presentation of this information facilitates decision-making (4) overall accessibility of information. These domains will be measured using a seven-point Likert scale (1 = strongly disagree, 7 = strongly agree). The statements will be: 'It was easy to find the information', 'it was easy to understand the information', 'the information was presented in a way that would help me make a decision', and 'this website was easy to navigate'. The investigators will calculate mean composite values of these four domains for the primary outcome of accessibility, and present the four individual domains as secondary outcomes.

Trial Information

NCT ID

NCT04745897

Status

Completed

Study Type

INTERVENTIONAL

Phases

NA

Sponsor

McMaster University

Last Updated

December 15, 2025