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Thymosin-alpha-1

Thymalfasin, Zadaxin, Thymosin α1

Quick Stats
Studies 759
Trials 63
Completed NA INTERVENTIONAL NCT00711620

Efficacy of Thymosin alpha1 for Severe Sepsis

View on ClinicalTrials.gov Updated Dec 15, 2025

Brief Summary

The purpose of this study is to evaluate the efficacy of thymosin alpha 1 for treating severe sepsis.

Detailed Description

Severe sepsis is a disease of infectious origin with a high risk of death. Over the past decade, thymosin alpha1 have already provided clinicians with additional weapon in the fight against infectious diseases, but it is unknown whether thymosin alpha1 is effective in treating severe sepsis.

Interventions

Name: Thymosin alpha 1
Type: DRUG
Description: 1.6 mg s.c injection twice per day for 5 days, then 1.6 mg s.c injection once per day for 2 days.

Primary Outcomes

Measure: 28-day Mortality
TimeFrame: 28 days
Description: The prospectively defined primary end point was death from any cause and was assessed 28 days after the start of the infusion.

Trial Information

NCT ID

NCT00711620

Status

Completed

Study Type

INTERVENTIONAL

Phases

NA

Sponsor

Sun Yat-sen University

Last Updated

December 15, 2025