Score
2
1984
pubmed
[Effects of thymosin alpha l on some time-dependent functions in thymectomized mice].
Baldassarre. A M AM; Mastino. A A; Del Gobbo. V V
Key Findings
- Synthetic thymosin‑alpha‑1 restored azathioprine‑sensitivity of spleen cells in thymectomized mice
- It revived thymic‑like activity in the serum of these mice
- The effect was observed after the peptide was administered in vivo
Practical Outcomes
- The study suggests thymosin‑alpha‑1 might help recover immune function after severe thymus loss, but it’s an animal model only. For biohackers, it signals a possible immune‑support role, yet no human dosing or safety data are available, so it isn’t ready for direct self‑experimentation.
Summary
In mice without a thymus, giving them a lab-made version of thymosin‑alpha‑1 helped bring back certain immune functions that were weakened, showing the peptide can boost T‑cell related activity after it’s taken in the body.
Abstract
The effects of a synthetic thymosin alpha1 on the azathioprine-sensitivity of spleen cells and on the thymic-like activity of serum from adult thymectomized mice, were observed. Thymosin alpha1 is able to restore the lowered levels of these T-dependent functions after in vivo administration.
Study Information
Provider
pubmed
Year
1984
Date
1984-01-30T00:00:00.000Z