Menu
Peptide Database
Results
No peptides found
Featured

Use search to browse all 100+ peptides

Tirzepatide

Mounjaro, Zepbound, LY3298176

Quick Stats
Studies 183
Trials 100
Completed PHASE1 INTERVENTIONAL NCT04311424

Study of Tirzepatide in Healthy Participants

View on ClinicalTrials.gov Updated Dec 15, 2025

Brief Summary

The purpose of this study is to look at how much tirzepatide gets into the bloodstream and how long the body takes to get rid of it. This study will involve a single dose of 14C radiolabelled tirzepatide. This means that a radioactive tracer substance, C14, will be incorporated into the study drug to investigate the study drug and its breakdown products and to find out how much of these pass from blood into urine, feces and expired air. Screening is required within 28 days prior to the start of the study. For each participant, the total duration of the clinical trial will be approximately 15 weeks, including screening.

Interventions

Name: 14C Tirzepatide
Type: DRUG
Description: Administered SC.

Primary Outcomes

Measure: Urinary Excretion of Tirzepatide Radioactivity Over Time Expressed As A Percentage of the Total Radioactive Dose Administered
TimeFrame: Pre-dose and up to 63 days post-dose
Description: Urinary Excretion of Tirzepatide Radioactivity Over Time Expressed As A Percentage of the Total Radioactive Dose Administered.
Measure: Fecal Excretion of Tirzepatide Radioactivity Over Time Expressed As A Percentage of the Total Radioactive Dose Administered
TimeFrame: Pre-dose and up to 63 days post-dose
Description: Fecal Excretion of Tirzepatide Radioactivity Over Time Expressed As A Percentage of the Total Radioactive Dose Administered.

Trial Information

NCT ID

NCT04311424

Status

Completed

Study Type

INTERVENTIONAL

Phases

PHASE1

Sponsor

Eli Lilly and Company

Last Updated

December 15, 2025