Topical manganese peptide in the treatment of photodamaged skin.
Hussain. Mussarrat M; Goldberg. David J DJ
Key Findings
- Hyperpigmentation and other signs of photodamage improved after 12 weeks of use.
- Overall photodamage rating shifted from moderate to mild.
- The peptide was well tolerated with no significant skin inflammation.
Practical Outcomes
- For biohackers interested in skin health, a twice‑daily topical serum containing Manganese Tripeptide‑1 for about three months appears to brighten sun‑damaged skin and fade dark spots without causing irritation. It can be added to a daily skincare regimen as a low‑risk, evidence‑backed option for improving skin appearance.
Summary
A facial serum with a manganese tripeptide applied twice a day for up to 12 weeks helped reduce visible sun damage and dark spots on the skin, moving the overall damage rating from moderate to mild, and it caused no irritation.
Abstract
This study evaluated the effects of a manganese peptide complex in the treatment of various signs of cutaneous facial photodamage. Individuals used a facial serum formulation containing the manganese peptide complex Manganese Tripeptide-1 twice a day for up to 12 weeks. At the end of the treatment period, the individuals and a blinded investigator noted improvement in the appearance of several signs of cutaneous photodamage. Predominant among the parameters showing improvement were those associated with hyperpigmentation. In general, at the end of 12 weeks of treatment, photodamage ranking moved from moderate to mild. Treatment was well tolerated with no significant cutaneous inflammation induced by the manganese peptide complex.
Study Information
pubmed
2007
2007-01-01T00:00:00.000Z
10.1080/14764170701704668
23
8