Completed
OBSERVATIONAL
NCT05969834
HCG Levels After Ovulation Triggering as Predictors of ICSI Outcome
View on ClinicalTrials.gov
Updated Dec 15, 2025
Brief Summary
This study aimed to assess the correlation between HCG levels after ovulation triggering and ICSI outcomes, affected by HCG formulation and dose
Detailed Description
The aims of this study are: 1. To assess the correlation between serum human chorionic gonadotropin (hCG) level after ovulation triggering and intracytoplasmic sperm injection (ICSI) outcome including: oocyte maturity and quality, good quality embryo rate, blastocyst formation rate and pregnancy rate 2. To determine if there is an association between type and dose of the trigger and ICSI outcome.
Interventions
Name:
uHCG
Type:
DRUG
Description:
Final oocyte maturation will be triggered by IM administration of 10000 IU of uHCG (Choriomon)
Name:
rHCG
Type:
DRUG
Description:
Final oocyte maturation will be triggered by SC administration of 6500 IU of rHCG (Ovitrelle)
Name:
uHCG and GnRHa
Type:
DRUG
Description:
Final oocyte maturation will be triggered by combined SC administration of 0.1 mg of GnRHa (Decapeptyl, Triptorelin) and IM administration of 2500 IU of uHCG (Choriomon)
Primary Outcomes
Measure:
Clinical pregnancy rate
TimeFrame:
6 weeks after embryo transfer
Description:
Number of clinical pregnancies (defined as presence of at least one intrauterine gestational sac with fetal pole and cardiac activity on TVS scan at 4-6 weeks after the ET) divided by the number of ET procedures
Trial Information
NCT ID
NCT05969834
Status
Completed
Study Type
OBSERVATIONAL
Sponsor
Mansoura University
Last Updated
December 15, 2025